BDBM50062351 (R)-N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-methylcarbamoyl-ethyl]-2-isobutyl-succinamide::(R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylcarbamoyl-ethyl]-2-isobutyl-succinamide::(R)-N1-((S)-3-(1H-indol-3-yl)-1-(methylamino)-1-oxopropan-2-yl)-N4-hydroxy-2-isobutylsuccinamide::3-(N-HYDROXYCARBOXAMIDO)-2-ISOBUTYLPROPANOYL-TRP-METHYLAMIDE::CHEMBL19611::Ilomastat::US9487462, ilomastat
SMILES CNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)CC(=O)NO
InChI Key InChIKey=NITYDPDXAAFEIT-DYVFJYSZSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50062351
TargetDisintegrin and metalloproteinase domain-containing protein 10(Homo sapiens (Human))
Department Of Life Science And National Research Laboratory Of Proteolysis
Curated by ChEMBL
Department Of Life Science And National Research Laboratory Of Proteolysis
Curated by ChEMBL
Affinity DataIC50: 8.10nMAssay Description:In vitro inhibition of A disintegrin and metalloproteinase domain 10 (ADAM10)More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 10(Homo sapiens (Human))
Department Of Life Science And National Research Laboratory Of Proteolysis
Curated by ChEMBL
Department Of Life Science And National Research Laboratory Of Proteolysis
Curated by ChEMBL
Affinity DataIC50: 263nMAssay Description:Inhibition of ADAM10 after 10 to 15 mins by fluorescence assayMore data for this Ligand-Target Pair